MS in the Age of Enhanced Therapeutic Options
PROGRAM DESCRIPTION Despite decades of progress in the management of relapsing-remitting multiple sclerosis (RRMS), notable challenges remain. With a growing armamentarium of treatment options, clinicians are faced with the need ...
Despite decades of progress in the management of relapsing-remitting multiple sclerosis (RRMS), notable challenges remain. With a growing armamentarium of treatment options, clinicians are faced with the need to understand the full range of risk-benefit profiles so as to select the most appropriate therapy based on individual patient characteristics. Of particular concern are the large numbers of patients who fail to respond adequately to initial treatment with a disease-modifying therapy (DMT). Prompt recognition of such patients is crucial to prevent the accumulation of disability and delay disease progression. Clinicians must have the requisite knowledge to identify clinical and MRI findings suggestive of a suboptimal response that necessitates switching to another treatment strategy. The process of deciding which DMT should be chosen when switching therapy mandates consideration of the mode of actions, efficacy and safety, and individual patient factors. Clinicians must be competent in addressing these issues if the best possible outcomes are to be achieved. The potential advent of additional treatments also highlights the need for clinicians to stay up to date on developments that may impact the management of RRMS in the future.
Upon completion of this educational activity, participants should be able to:Explain the mechanisms of action of available and emerging multiple sclerosis (MS) therapies as well as implications for treatment selectionDiscuss the efficacy and safety of current treatments for MS and available data on investigational therapiesReview perspectives on MRI and clinical findings that may prompt consideration of switching therapy for MSAnalyze knowledge about MS therapies and aspects of a patient’s presentation to make an informed decision when switching MS therapies
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