Selecting a Biologic for Long-Term Success in UC

PROGRAM DESCRIPTION The traditional goal of therapy for ulcerative colitis (UC) is the induction and maintenance of (steroid-free) clinical remission. Mucosal healing has assumed increasing importance, due to the association ...

PROGRAM DESCRIPTION
The traditional goal of therapy for ulcerative colitis (UC) is the induction and maintenance of (steroid-free) clinical remission. Mucosal healing has assumed increasing importance, due to the association with fewer relapses, and reduced risk of surgery and hospitalization. Choosing the ‘right’ goal for any patient requires balancing the patient’s needs with clinical efficacy and consideration of risks and costs. When selecting a biologic therapy there are no data to recommend a ‘one size fits all’ approach, therefore several aspects should be taken into consideration, such as the clinical evidence, disease severity and patient characteristics and preferences. This module presents some of the clinical evidence for biologic therapy in UC, including ‘real-world’ and long-term data, and discusses relevant factors to consider when selecting a biologic agent for a UC patient.

EDUCATIONAL OBJECTIVES
Upon completion of this activity, participants should be better able to:Distinguish short-term needs (symptomatic improvement with minimal side effects) from long-term goals (continuous steroid-free clinical remission with documented mucosal healing) of therapy in UCSelect biologic therapy that aligns with individual patient needs to minimize risk of treatment discontinuation

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