Shifting Paradigms in Primary Biliary Cholangitis

PROGRAM DESCRIPTION In this video series, Kris Kowdley, MD, and Seth Sclair, MD, share insights into changes in the management of patients with primary biliary cholangitis. This progressive, autoimmune disease ...

PROGRAM DESCRIPTION
In this video series, Kris Kowdley, MD, and Seth Sclair, MD, share insights into changes in the management of patients with primary biliary cholangitis. This progressive, autoimmune disease was previously referred to as primary biliary cirrhosis. One notable change discussed is approval of obeticholic acid for use in adults with an inadequate response to ursodeoxycholic acid, or as monotherapy in adults unable to tolerate ursodeoxycholic acid.Topics discussed include:Diagnostic considerationsInitial treatment with ursodeoxycholic acidAssessing response to ursodeoxycholic acidObeticholic acidInvestigational treatmentsManaging symptoms and complications

EDUCATIONAL OBJECTIVES
At the conclusion of this activity, participants should be better able to:Identify patients with primary biliary cholangitis (PBC) at the earliest stage of diseaseInitiate first-line treatment with ursodiol in appropriate patientsAssess response/nonresponse to ursodiolSelect second-line therapy based on available evidenceInitiate obeticholic acid in appropriate patientsInitiate evidence-based treatment to manage symptoms and complications

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